Saturday, December 13, 2008

Important Update to Folding@Home's End User License Agreement (EULA)

Vijay Pande has posted on his blog a very important notice about an update to the Folding@Home End User License Agreement (EULA).

Straight from Vijay:
"We added the word "written" to this sentence:

"You may use this software on a computer system only if you own the system or have the written permission of the owner."

We felt that this was an important addition in order to avoid any confusion. There have been a few situations where donors felt that they had permission, but the owners of the computers did not. Having written permission is the best way to make sure that there is no doubt. It also gives protection to the donor in that he/she would then have proof of permission, avoiding problems involving oral agreements."

I'd like to re-affirm that you could find yourself in a situation of getting sued for installing and running this program unauthorised, as many people have gotten into trouble setting up multiple computers at they're place of work (such as a school I.T. Administrator setting up tens to hundreds of computers) when they weren't authorised to do so, and have in some cases been ordered to pay damages for things such as increases in power bills, internet bills etc. Also, not having sufficient knowledge about the program and how it can affect different computers etc. (such as Notebooks being advised to run at no more than 90% CPU usage due to their less than optimal cooling systems) can lead to a bit of a blame game as far as what caused the computer to pack itself in and who is going to pay for it!

So guys, make sure you get written consent to run Folding@Home on computers or machines that are not your own. And be sure to inform those owners or bill-payers of the potential to have slightly higher power and internet bills whilst running this program (not a big deal for one or two machines, but any more, the extra power and internet usage quickly adds up!). Providing you do the right thing by the owner, i'm sure they will enjoy helping out a Distributed Computing Project such as Folding@Home.

New Paper published on the Playstation 3 Folding@Home client

Vijay Pande's blog yet again brings good news with yet another Paper being published, this time about the Playstation 3 Folding@Home client - Accelerating Molecular Dynamic Simulation on the Cell processor and PlayStation 3.

A collaborated effort between the Folding@Home and Sony Development teams, this is the first paper resulting from the Playstation 3's involvement in the Project. The paper is more of a 'how does it work' with details about how the PS3 accelerates simulations through use of it's powerful streaming processor, the CELL Broadband Engine.

The abstract reads:
"Implementation of molecular dynamics (MD) calculations on novel architectures will vastly increase its power to calculate the physical properties of complex systems. Herein, we detail algorithmic advances developed to accelerate MD simulations on the Cell processor, a commodity processor found in PlayStation 3 (PS3). In particular, we discuss issues regarding memory access versus computation and the types of calculations which are best suited for streaming processors such as the Cell, focusing on implicit solvation models. We conclude with a comparison of improved performance on the PS3's Cell processor over more traditional processors."
Papers of this type not only help the Folding@Home team at Stanford, but can potentially help many others outside of the Project. Whether it helps out others involved in the field of Molecular Dynamics, or people that intend to use and program for the CELL processor, knowledge gained can be knowledge shared!

Work Units Milestone - ROO_BOY29 - 50

ROO_BOY29 has made the milestone for 50 work units!

Due to a bit of downtime, after needing a re-format/re-install, his computer unfortunately didn't tally any points for our recent November = 2nd Team Birthday Foldathon. However, his got 4 services of v5.04 text-only console client running on his quad-core again, and should see a pretty consistent return from him now.

Currently on 13,736 points from 50 work units, he sits 186,173rd out of 1,149,041 all-time folders. Well done mate.

New Team Member - brolli55_ps3

We have a new team member! Another one of my mates - brolli55_ps3 has joined the team currently folding with his Playstation 3. brolli55 will also appear on the team stats soon, as we await his computer to return it's first work.

With one work unit currently to his name, brolli55_ps3 has made 450 points, and sits 729,857th out of 1,149,041 all-time folders. Good stuff mate.

Thursday, December 11, 2008

Another new Paper! Ribosome Gate

Only on Tuesday Vijay Pande announced on his blog that the Project published New Alzheimer's Disease Work. Now another paper, Folding@Home's 59th to be exact, has been published - 'Side-chain recognition and gating in the ribosome exit tunnel'.

The Ribosome plays a very important role in Protein research says Vijay:
"The ribosome is a fascinating molecular machine, responsible for the synthesis of proteins. For this reason it is of fundamental importance to protein folding (as the last step in the central dogma of biology) as well as to human health (since the ribosome is the target of a very large fraction of antibiotics)."
Vijay mentions that this paper has been made possible by the contributions of folders running 'bigWU' enabled classic clients stating:
"the ribosome is so huge that it would not run on regular classic clients."
It's certainly good to see a couple more important research papers come out lately, and only a day after another! I can't wait to see what other papers get released and how they can help us move forward in the Protein research field.

Points Milestone - Lahm_Family_PS3 - 100k

My 2nd Playstation 3 - Lahm_Family_PS3 is the 5th team member to achieve the 100,000 points milestone! Thus moving up a category in the Major Milestone Club.

Joining the team in late August, I was hoping to gain atleast 100k points by the end of the year, so i'm very happy it's achieved that. Pretty much folding 24/7 (with only occassional power outages and a bit of music playing in between), it wasn't overly hard to achieve. Now I want to set a target of 300,000 points by 27 August 2009.. which would mean a tidy 300k points per year.

Currently on 100,383 points from 343 work units, it's sits 5th on the team leaderboard, and 45,147th out of 1,147,479 all-time folders. No doubt i'll keep her folding as much as possible!

Top 10 Team Members Shuffle

Racing up the Team Leaderboard, Ugly has brought about another shuffle in the top 10 order, this time by moving to 7th spot, overtaking zoneur who now sits at 8th.

Current top 10 order:

Team members
Rank
(within team)
User Score WU
1 smASHer88_PS3 293785 1189
2 Jens_Klausen 265299 569
3 Ravenge5 166003 745
4 RoXeD 132100 543
5 Lahm_Family_PS3 100383 343
6 peterdiva 94067 152
7 Ugly 66590 69
8 zoneur 65715 145
9 smASHer88 56240 193
10 BulleenAnt1 42574 145

Tuesday, December 9, 2008

New Alzheimer's Disease Work published

The latest news from Vijay Pande's blog is about the publication of a key paper relating to Alzheimer's Disease - 'Simulating oligomerization at experimental concentrations and long timescales: A Markov state model approach'.

Vijay comments saying:
"I am very happy to announce that a first key work from the Folding@home project on Alzheimer's Disease (AD) was just published"
"In many ways, this paper is the "tip of the iceberg" for the Folding@home activities in AD, with a lot more interesting results to come, especially in terms of experimental tests of our predictions and interesting new possibilities for new drugs and AD therapeutics. So, while we're excited that this result is now past peer review, we're even more excited for what's coming down the pipeline, waiting peer review. We'll keep you posted as more results become public, hopefully with some even bigger announcements in 2009."
Hopefully this will mean Folding@Home as a Project will start to see some real fruit for all it's labour!

UPDATE:
"It was asked which clients participated. This work started several years ago and took some time to analyze and then publish. So, it ran exclusively on classic clients. For the follow up simulations, we are using a mixture of GPU, SMP, and classic clients. Due to the large number of classic clients, they allow us to calculations not possible on the other platforms. However, the raw speed (but smaller number) of the GPU and SMP clients allow us to get a good rough idea quickly, refining later with classic clients."

Sunday, December 7, 2008

Top 10 Team Members Shuffle

With the latest change to the Top 10 Team Members order, Ugly has now moved to 8th spot on the team leaderboard, overtaking my computer - smASHer88, which is now at 9th spot.

Current top 10:

Team members
Rank
(within team)
User Score WU
1 smASHer88_PS3 290635 1178
2 Jens_Klausen 251679 538
3 Ravenge5 166003 745
4 RoXeD 132100 543
5 Lahm_Family_PS3 97053 333
6 peterdiva 89374 132
7 zoneur 65715 145
8 Ugly 57770 54
9 smASHer88 55491 192
10 BulleenAnt1 42445 144

Work Units Milestone - Ugly - 50

Ugly has now returned 50 work units to claim his first work units milestone.

Currently on 55,040 points from 50 work units, he's 9th on the team leaderboard, and 73,169th out of 1,145,122 all-time folders.

Saturday, December 6, 2008

Points Milestone - Ugly - 50k

Ugly joins eight other team members on the Major Milestone Club list for achieving the milestone for 50,000 points!

Since joining the team in late October, Ugly has managed to gain 51,950 points from just 45 work units! How? Well as you'll read in joining post, he has been running the SMP client on an Apple MacBook Pro, which usually fetches him between 1,000 and 2,000 points per work unit! Of course his points to work unit ratio show hes much closer to 1,000 points / work unit. This could be because he's recently added a PS3 to fold under Ugly as well, bringing his average points per work unit down.

He currently sits 9th on the team leaderboard and 76,306th out of 1,144,455 all-time folders. Well done mate.

Thursday, December 4, 2008

Work Units Milestone - Jens_Klausen - 500

Jens_Klausen has become the 4th team member to make the 500 work units milestone as he bumps himself up a category in the Major Milestone Club!

Since joining nearly three months ago, he has returned exactly 506 work units for a total of 237,864 points. This means he has contributed approximately 15% of the team's points, and nearly 10% of all work units!

He's currently coming 2nd on the team leaderboard, and could easily overtake my main PS3 - smASHer88_PS3 just after New Years! He sits 19,715th out of 1,143,682 all-time folders. Well done mate.

Where Folding@Home is heading

Vijay Pande has posted a 'Long term vision' on his blog about Folding@Home about where it is heading and what sort of results we can expect Science wise.

He mentions the fact that the first few years of the project was spent working out the right types of methods to use to enable a functional Distributed Computing network.

The next step was to work in the latest range of clients (Playstation 3, SMP and GPU) which has been a big task to accomplish and still not perfected as of yet. An 'SMP2' client is the next target for the development team, with hopes that it will be similar to the transformation of the GPU to GPU2 client. Vijay comments saying -
"Our goal is to be bleeding edge in the nature of our science, but get back to the simplicity and stability found in the classic client"
Science wise, we are to expect some pretty big results very soon, with many research papers to be published after peer review is completed. Vijay comments -
"In particular, results on Alzheimer's Disease, Huntington's Disease, and some other surprises in the works"
So there you go guys, the real reason we are all folding hasn't been forgotten. Hopefully a lot can be learned from these future publicly-released research papers, and we can see the benefit gained from lending our CPU cycles!

Points Milestone - Jawgz - 20k

My mate Jawgz has now hit the 20,000 points milestone!

In addition to his Mac, he's now got some computers at work crunching away for him as well! Sitting on exactly 20,966 points from 29 work units, he sits 15th on the team leaderboard and 143,102nd out of 1,143,038 all-time folders. Good stuff mate!

Wednesday, December 3, 2008

Monday, December 1, 2008

2nd Team Birthday Foldathon! Results

As we finish our 2nd Team Birthday Foldathon, we look back at some interesting stats that have happened just over the month of November.

A total of 376,655 points was generated by Aussie Rules Footy in November by returning a total of 884 work units. Our team ranking position has advanced 199 places up to 1,080th! (previously 1,279th).

We've seen eleven changes to the top 10 team leaderboard, and two changes in the top 5 order. We've had a few work unit milestones - three 100, two 200 and a 5k for the team. Also, for points milestones, we've had three 5k, two 10k, four 20k, two 50k, one 100k and one 200k. We've also brought in a new team logo, had two new team members join, and have had some interruptions to our foldathon in the form of server troubles.

But past all that, we

EDIT:
WILL UPDATE AS SOON AS I HAVE ENOUGH FREE TIME TO WRAP UP THIS HUGE POST, SORRY!

Winner: Jens_Klausen - 144,096 points from 306 work units, averaging 4,803 PPD




Aussie Rules Footy

Date of last work unit 2008-11-30 06:44:37
Active CPUs within 50 days 39
Team Id 52735
Grand Score 1483416 (certificate)
Work Unit Count 5286 (certificate)
Team Ranking (incl. aggregate) 1080 of 148592
Home Page http://team52735.blogspot.com/
Fast Teampage URL http://fah-web.stanford.edu/teamstats/team52735.html


Team members
Rank
(within team)
User Score WU
1 smASHer88_PS3 284585 1155
2 Jens_Klausen 229004 486
3 Ravenge5 166003 745
4 RoXeD 132100 543
5 Lahm_Family_PS3 90273 314
6 peterdiva 75820 113
7 zoneur 61625 135
8 smASHer88 55491 192
9 BulleenAnt1 42274 143
10 Ugly 39450 21
11 DSE_352_PS3 37070 138
12 DSE_352_Notebooks 33652 137
13 mikael 26502 127
14 QCKRNU 24728 153
15 BIGMAN 20343 58
16 Delta_Leviathan 18817 132
17 Jawgz 16992 25
18 Greg 16622 114
19 magicgate3 15835 66
20 ROO_BOY29 13055 46
21 ahmsnake 11179 45
22 savernake 9445 38
23 Jacko 7230 36
24 rossqo 6186 13
25 Ravenge 6090 38
26 mgpower0 5280 3
27 bec_clarke 4413 41
28 PS3 3982 33
29 hobbozzrock 3685 15
30 MitchAllen 3614 42
31 nitty 3080 5
32 erBotty 2250 5
33 J4CKT 2220 9
34 BOONDOCKS 1500 1
35 TheePi 1388 36
36 ningcaptor 1036 9
37 terminator80 960 2
38 luigi4562 953 7
39 Rfscann 935 6
40 Suzy_Wong 837 4
41 SHELL86 765 2
42 CCz619 625 5
43 Bennymac 598 4
44 wilson 545 2
45 QUEBEC 500 2
46 Bioufaxxx 500 3
47 Revolutionary_For_Life 372 2
48 goddest 340 1
49 NTC 313 2
50 PS34LIFE.ZACHZEHRUNG 287 1
51 KillerKahuna 287 2
52 Curer_Of_Diseases 256 3
53 naomi 250 1
54 captinmax 250 1
55 nigel 250 2
56 Beauwoodland 186 1
57 chris_be 186 1
58 J4CKT_PC 149 3
59 Shinobi 125 1
60 dcbunny 98 2
61 Jorgo 30 2
62 THAmyth 0 4
63 ronnie 0 3
64 Bernard 0 5

PPD = Points Per Day

Sunday, November 30, 2008

New Top 10 Team Member - Ugly

Congratulations to Ugly who has now joined the Top 10 on the Team Leaderboard knocking DSE_352_PS3 back to 11th!

Here's how the current top 10 stands:

Team members
Rank
(within team)
User Score WU
1 smASHer88_PS3 283685 1152
2 Jens_Klausen 225613 478
3 Ravenge5 166003 745
4 RoXeD 132100 543
5 Lahm_Family_PS3 89463 311
6 peterdiva 73608 111
7 zoneur 61625 135
8 smASHer88 55491 192
9 BulleenAnt1 42274 143
10 Ugly 38557 20

Saturday, November 29, 2008

Folding@Home Server changes plan to reduce downtime

Vijay Pande has posted some news on his blog about recent changes regarding the Collection Servers (CS), and also about plans for Server upgrades in the near future.

The Collection Servers have gotten a bit of tweaking, and have been moved onto a new network as the old one has had quite a few problems. Both Servers (171.67.108.17 & 171.67.108.25) are reportedly doing well for now. These servers act as backups when the Work Servers (where you download work units from) can't handle all the completed/uploaded work units, or when they are down.

The Folding@Home team also plan to issue general server upgrades with v5 code (currently in beta testing with Project 3798) early next year, with production Work Servers likely to be updated starting in January. This v5 code is being built from scratch and hopefully will result in much more stable servers for a more reliable Project network.

Thursday, November 27, 2008

New Team Member - terminator80

A new team member going by the name of terminator80 has joined our team.

Already returning 2 work units, they have earned 960 points so far and sit 584,890th out of 1,137,792 all-time folders.

Tuesday, November 25, 2008

Points Milestone - Jens_Klausen - 200k

Joining smASHer88_PS3 in the 200k points Team Member Major Milestones Club category, Jens_Klausen is now the second team member to crack the 200,000 points milestone!

Only joining the team just over two months ago, Jens_Klausen has made a significant contribution to the team's total points in such a short time. Using 2 x GPUs to fold, he cranks out over 4,000 points daily! Now sitting on 205,679 from 433 work units, he's sitting 2nd on the team leaderboard and 22,452nd out of 1,136,995 all-time folders. Well done mate!

Monday, November 24, 2008

Top 10 Team Members Shuffle

Our most recent change to our Team Leaderboard Top 10 sees zoneur move ahead to 7th spot, pushing my computer - smASHer88 back to 8th.

The current top 10:

Team members
Rank
(within team)
User Score WU
1 smASHer88_PS3 277478 1129
2 Jens_Klausen 193199 407
3 Ravenge5 166003 745
4 RoXeD 132100 543
5 Lahm_Family_PS3 83243 287
6 peterdiva 61671 100
7 zoneur 55834 122
8 smASHer88 55491 192
9 BulleenAnt1 42274 143
10 DSE_352_PS3 37070 138

Work Units Milestone - peterdiva - 100

peterdiva has made a milestone for returning 100 work units!

Gaining 61,671 points from those 100 work units, he sits 6th on the team leaderboard, and 65,642nd out of 1,135,251 all-time folders. Well done mate.

Sunday, November 23, 2008

Points Milestone - Ravenge - 5k

Ravenge5's computer, running as Ravenge has just broken through the 5,000 points milestone!

Currently on 5,283 points from 35 work units, his computer sits 299,565th out of 1,134,191 all-time folders. Good stuff mate!

New Team Member - NTC

Please welcome our newest member to the team - NTC.

They've already returned their 1st work unit for 114 points and they currently sit 928,174th out of 1,134,191 all-time folders.

Main Assignment Server was down temporarily

Reading Vijay Pande's blog (posts 1 & 2), it seems the Main Assignment Server was out of action for approximately an hour, which wasn't to worry as they have other backup servers in place for times like these. This all happened at approximately 4:30 PM PST November 21 (so just before lunch, 11:30 AM AEDT, November 22 here on the Aussie East Coast!)

The main consequence is that the Stats system had to hold off updating for a while, so the Team/Donor stats might not have appeared to update for a few hours. All work unit credits were still counted, but they just might have taken a while to get credited to the Stats system. All should be good now.


PST = Pacific Standard Time = UTC-8
AEDT = Australian Eastern Daylight Time = UTC+11

Saturday, November 22, 2008

Points Milestone - QCKRNU - 20k

QCKRNU has now made the 20,000 points milestone!

Using his dual-core AMD processor, he's returned 134 work units so far for a total of exactly 20,053 points. Sitting 15th on the team leaderboard, he sits 145,347th out of 1,133,297 all-time folders. Great stuff mate.

Points Milestone - Jawgz - 10k

Jawgz has now passed the milestone for 10,000 points!

Sitting on 11,007 points from only 21 work units, he sits 21st on the team leaderboard and 206,995th out of 1,133,297 all-time folders. Well done mate.

Work Units Milestone - Aussie Rules Footy - 5k

We as a team have now collectively returned over 5,000 work units!!!

We currently sit on 5,041 work units which has earned us a total of 1,366,048 points so far. We sit 1,136th out of 147,872 all-time teams. Well done guys, we have contributed a great effort to Folding@Home so far, and we should be at 10,000 work units in no time!

Friday, November 21, 2008

Top 10 Team Members Shuffle

With another change to our Top 10 Team Members, peterdiva now jumps to 6th spot, pushing my computer - smASHer88 back to 7th.

There's been a lot of changes on team leaderboard just in November, and I can't wait to see where everyone sits at the end of 2008! Heres the current top 10:

Team members
Rank
(within team)
User Score WU
1 smASHer88_PS3 274698 1118
2 Jens_Klausen 173999 367
3 Ravenge5 166003 745
4 RoXeD 132100 543
5 Lahm_Family_PS3 80133 275
6 peterdiva 56927 96
7 smASHer88 55199 191
8 zoneur 51514 113
9 BulleenAnt1 42274 143
10 DSE_352_PS3 37070 138

Points Milestone - zoneur - 50k

zoneur has now passed the milestone for 50,000 points!

Our 8th team member to do so, he joins seven others on the Major Milestone Club for passing 50k points. He now sits on exactly 51,514 points from 113 work units. Currently 8th on the team leaderboard, he's running 75,227th out of 1,132,309 all-time folders. Congrats mate!

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